Systemic Lupus Erythematosus (SLE)

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About Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease in which the immune system mistakenly attacks the body’s own tissues and organs, causing inflammation and damage. It can affect multiple organ systems, including the skin, joints, kidneys, heart, lungs, brain, and blood cells. SLE is the most common and severe type of lupus and is characterized by periods of flares and remissions. Common symptoms include fatigue, joint pain, skin rashes (such as the characteristic butterfly rash), and kidney issues. SLE can vary in severity, with treatment focused on managing symptoms and reducing inflammation. While SLE is a lifelong condition, early diagnosis and effective management allow many people with the disease to live relatively normal lives, though some may experience serious complications over time.

About our SLE Registry

The SLE registry prospectively collects detailed patient-level data, enabling assessment of the natural history of the disease, treatment patterns, real-world safety of medications used, disease burden and unmet needs in patients living with SLE. Granular, longitudinal outcome measures are collected during regular visits, including clinician-reported SLE outcomes, biologics and lab measures, and patient-reported outcomes assessing symptom impact and quality of life.

Read the press release, here.

Clinical outcome measures and PROs in the CorEvitas SLE Registry

Among the variables we collect, some of the key outcome measures to inform your research include:

Clinician-Reported Outcomes

Patient-Reported Outcomes

Registry Scientific Advisors

Picture of Anca Askanase, MD, MPH​

Anca Askanase, MD, MPH​

Clinical Director, Lupus Center & Director, Rheumatology Clinical Trials​
Professor of Medicine, Columbia University Medical Center​

Picture of George Tsokos, MD​

George Tsokos, MD​

Chief, Division of Rheumatology​
Beth Israel Deaconess Medical Center​
Professor of Medicine, Harvard Medical School​