Real-World Evidence
Embracing the power of real-world insights to drive innovation
Evidence of safety, effectiveness and value is critical to achieve successful market access and product uptake. The expanding acceptance of real-world evidence (RWE) by regulators, health technology assessment (HTA) bodies and payors, combined with the demand of patients and health care providers (HCPs) for greater transparency into product benefits and risks in real-world use, is revolutionizing RWE generation and use.
Real-world evidence research is applied at every stage of the product life cycle, meeting needs from early discovery through post market. Because clinical trial data are no longer sufficient in obtaining product approval, market access or patient use, RWE complements these data by providing real-world context and broader patient representation, allowing more accurate assessment of comparative effectiveness, safety outcomes and long-term real-world benefits.
By aligning clinical and real-world needs, the PPD™ clinical research business of Thermo Fisher Scientific brings together the right solutions to identify the right evidence for the right audience at the right time. Harness the power of real-world data (RWD) to unlock vital insights that inform decision-making, enhance patient outcomes and drive innovation.
Put real-world evidence to work for you.
Real-world evidence to inform decision-making
The value of RWE insights begins in early development—often before clinical trials even begin—and continues well past market access.
Real-world evidence benefits every step in your development path by:
- Informing clinical trial design, improving patient recruitment, and identifying and optimizing endpoints for more efficient and successful clinical trials
- Assessing comparative effectiveness, safety outcomes and long-term real-world benefits to enhance the understanding of a drug’s real-world impact
- Enabling proactive monitoring, risk management and timely safety interventions to ensure patient safety in the real-world setting
- Informing post-approval commitments, label expansions and regulatory assessments of safety, effectiveness and risk-benefit profiles
- Informing value-based pricing, reimbursement decisions and HTAs through outcomes analysis and resource utilization
- Facilitating shared decision-making, treatment optimization and personalized care to improve patient outcomes and satisfaction
- Identifying barriers to patient uptake in the real world to anticipate and mitigate challenges for optimal use and success
Address your most challenging research questions across the development life cycle with fit-for-purpose solutions identified and implemented by our multidisciplinary global team of experts.
Observational studies
The value of real-world evidence is dependent on scientifically rigorous study design and result interpretation. Observational (or non-interventional) studies are used to generate the right data to answer specific research questions. Ensure your study effectively meets your needs, whether focused on feasibility, clinical trial design, real-world safety or product effectiveness.
Learn more
Comprehensive, proprietary longitudinal data
Generate invaluable information on patterns in treatments and outcomes to inform decision-making, research, best practices and treatment protocols to advance patient care using proprietary PPD™ CorEvitas™ Registries.
These unique independent longitudinal registries capture robust, regulatory-grade clinician- and patient-reported data.
Learn moreData and scientific solutions
Real-world data sources are growing exponentially as technology advances and stakeholders encourage the use of RWE. Whether generating data through new studies or accessing existing secondary RWD, the real insights come from applying data science and analysis to raw data. Discover the power that real-world data evidence holds to enable insightful decision-making, provide impactful evidence and advance your product.
Pregnancy and lactation studies
Available data on the benefits and risks of medications in pregnant and lactating people have been historically insufficient, given they are rarely included in clinical trials. Regulators are increasing their guidance for and emphasis on real-world studies to understand the safety and efficacy of interventions in these important subpopulations. Generate comprehensive evidence to support the use of your product in these individuals and empower health care providers and patients to make informed health care decisions for themselves and future generations.
Patient-centered research
Engaging and including patients throughout the drug development process continues to be a priority for all stakeholders, with increased attention to and requirements for the inclusion of patient insights in the clinical trial design, approval, and market access processes.
Establishing a solid patient-centric approach to trial and study designs enables the effective integration of patient perspectives, preferences and outcomes into crucial decisions throughout the product journey. Improve outcomes with insights from the ultimate stakeholder―patients.
Learn more
Implementation science
Obstacles to product uptake in the real world always exist, with some products facing more challenges than others. Anticipate and proactively address barriers before they affect your product’s uptake. Implementation science uses innovative research approaches to close the gap between clinical research and real-world utility. Achieve real-world product optimization and usage with vital insights from every stage of development that impact your product’s ultimate success.
Learn moreSucceed with real-world experience
Take advantage of all the benefits RWE has to offer. With almost 40 years of experience providing expert strategic and scientific guidance, evidence planning and analysis, tailored study designs, and insightful quality results, the Evidera Real-World Evidence team enables our clients to deliver life-changing interventions to patients who need them.
When you partner with us, you can be confident knowing you are benefiting from:
Let’s partner to bring evidence to life
Get started with our real-world, patient-centric solutions.